anyone have experience with auto-immune disorders?

Maybe it was vonWillebrands-my Corgi was only 8. Has anyone else had experience with a sudden onset of loss of appetite, severe anemia, enlarged spleen? Her spleen was destroying her RBCs faster than her marrow could make them. First notable symptom besides lethargy and decrease appetite was a soft bright orange stool and dark urine. This was how her destroyed rbc's were eliminated.

If anyone sees this-RUN to your vet quickly! She died in less than a week.

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Am very sorry about your loss.

My Pembroke Welsh Corgi was diagnosed with Immune Mediated Thrombocytopenia - his body was attacking his own platelets. The first vet missed it, so we took him to another vet who ran all sorts of tests, and found the problem before it was too late. He had under 3000 platelets left when they finally hospitalized him. That was about three years ago. Luckily the vet was able to treat him and after a lot of ups and downs, he is doing OK..

I am so sorry to hear about your loss with this type of disease. It hits very fast and can go downhill very quickly.
I am so sorry to hear of your loss. We too lost our beloved Ace to auto immune disorder in April '07. Ace was a mix Pembroke Corgi/Brussels Griffon and two months from being 7 years old. With Ace there were no signs until the day he passed away. He was perfectly fine, at least he appeared to be, the day before. He was acting like his normal self. One morning he woke up and didn't seem to be interested in anything. I let him out for his "potty time", which also seemed normal, and then brought him inside. I had to coax him up the front step, he didn't want to move. Then he didn't even want his morning bisquit or breakfast, that was my first clue something was wrong. He just curled up on his blanket on the couch. I had an appointment and was gone for two hours. When I came home he was still on the couch, on the other end though. When I picked him up and put him on the floor he stood for about 15 seconds and then fell over. I called the vet and rushed him to them. They did tests and said that he was suffering from this auto immune disorder. When we arrived at the vet it was about noon, the vet told us to go home around 5 pm and he would watch him all night and we could come see him in the morning. The vet called an hour after we got home and said he passed away. That was so unexpected. Even the vet thought he would snap out of it. The vet told us that it is known as the uncommonly/common dissorder because it is actually fairly common but people really don't know about it. He also said it usually happens at about mid-age. I guess there are actually meds they can put them on if it is caught early enough, but then how do you know to check for it if there are no signs. Ace's gums were very pale, this was the only other sign we had other than being lethargic. As you said, if anyone experiences any of these symptoms get to the vet right away, hopefully they will be able to save your pup.

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